El Al partners with Alaska Airlines so flights can be credited to Alaska which makes it the best place to post these miles. These would credit at 125% EQMs and 200% RDMs.
MXP-TLV-JNB: 15208 EQMs and 24332 RDMs
You can add unlimited stopovers in Tel Aviv so in effect you can have 3 vacations in one fare. First you fly from Milan to TLV, then a Stopover in Israel and then fly on vacation/work to South Africa on the return you can either connect directly or have another stopover and then another vacation from TLV to Milan.
El Al Business Class Boeing 789