Nice sale with Aeromexico for travel between Los Angeles and Sao Paulo via Mexico City. This sample trip would allow you to collect a significant number of MQDs.
You can schedule some long layovers in Mexico City which would allow you to explore the city since you can reach the Zocalo via metro, 45 minutes to an hour both ways and see the Cathedral, National Palace and Rivera Murals, and the Templo Mayor or if you have some more time you can venture out to Teotihuacán which is an ancient Mesoamerican city located 30 miles (50 km) northeast of modern-day Mexico City.
LAX-GRU would earn 18495 MQMs 4932 MQDs 2.47 MQD Ratio while Delta Diamond members would obtain 39456 RDMs, Platinum 34524 RDMs, Gold 32058 RDMs, Silver 29592 RDMs, Base 24660 RDMs
For those collecting status with Air France/FlyingBlue you would obtain 90 XPs (30 XPs for GRU-MEX and 15 XPs each way for MEX-LAX)